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The key feature highlighted here is that little loss in activity was shown from three different enzymes comparing to those from conventional immobilization using pre-purified enzymes, suggesting that direct immobilization can also simplify the immobilization protocol
Finally, the customized microarray platform for DNA methylation analysis in CHO cells successfully validated adaptation-dependent epigenetic changes

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(v) participation in the maturation of ironsulfur cluster in proteins

Multi-week culture studies examining collagen, elastin, and proteoglycan gene expression often require repeat dosing of cultures across several passages, which draws down stock material more quickly than a single-endpoint assay
