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Vandooren, J., Opdenakker, G., Loadman, P

Antioxidant effects of sulfur-containing amino acids

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PKC further activates NADPH oxidase, producing large amounts of ROS and activating the NF-B and AP-1 pathways, thereby forming a positive feedback loop of ROS and inflammation (51)

PET bloodflow studies show that VNS acutely activates a distributed set of deep and cortical regions, with increased perfusion in the thalamus, hypothalamus, and insular cortex, and relative reduction in limbic regions like the amygdala and hippocampus, and some of these changes persist after months of therapy (Carron et al