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Nobiletin, a citrus flavonoid, inhibits hepatic lipid accumulation and decelerates the progression of NAFLD by regulating M1/M2 macrophage polarization through enhanced autophagy and by suppressing the NLRP3 inflammasome, a critical contributor to inflammatory cell death (210)

[PubMed: 16619056] 141

Specifically, effects of chemotherapeutics on the innate (Kiguchi et al., 2008

10.1089/ars.2010.3114 74 ConradM.SchickJ.AngeliJ

Gently massage until the cream is fully absorbed into your skin
