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The first study to indicate that pediatric use of APAP is associated with ASD was a survey-based, case-controlled study published by Schultz et al

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doi: 10.3389/fphar.2025.1639698 Received 02 June 2025 Revised 11 October 2025 Accepted 20 October 2025 Published 21 November 2025 Volume 16 - 2025 Edited by Maria Yelshanskaya, Columbia University, United States Reviewed by Linda Marie Nowak, Cornell University, United States Yue Zeng, Chinese Academy of Sciences (CAS), China Updates Copyright 2025 Garca-Daz, Castellanos, Miguez-Cabello, Picaol, Prez-Gonzlez, Gratacs-Batlle, Vega-Castro, Altafaj, Reyes-Guzmn, Reyes-Montao, Gasull and Soto

In the diabetic retina, oxidative stress increased and MnSOD attenuated, indicating the imbalance between oxidation and antioxidation

Adenomatoid change/glandular metaplasiafocal or diffuse proliferation of epithelial cells forming glandular structures