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From the time-course increase of the absorbance at 405 nm, derived from the enzymatic activity of SEAP, the activity of SEAP (in U/L) was determined
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Pro-inflammatory adipokines (e.g., leptin, resistin) and adipose-derived exosomes (carrying miRNAs like miR-3074-5p) create a chronic inflammatory joint microenvironment by polarizing synovial macrophages toward an M1 phenotype and inhibiting anti-inflammatory adiponectin (1618)
