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Class i nLDs likely form from the INM (see Fig 2H) and split the peripheral heterochromatin (blue) from the lamina

EPO is also believed to increase the risk of adverse health effects, but this has mainly been based on athletes anecdotal evidence and clinical studies in non-sports patients with other medical conditions

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Notably, PD primarily presents as a sporadic disease, but dedicated research efforts in genetics, epidemiology, neuropathology, and innovative experimental models have illuminated crucial insights into its development and progression (Moore et al., 2005)