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The development of gut hormone dual- and triagonists holds promise for treating obesity and T2DM with a level of effectiveness comparable to bariatric surgery

doi: 10.1016/j.ebiom.2019.10.023, 25

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Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) recognizes peptidoglycans from the bacterial wall and suppresses commensal bacteria extension, such as Enterobacteriaceae, Clostridiales, and Bacteroides spp