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Accumulation of lipid peroxides drives ferroptosis Polyunsaturated fatty acids (PUFAs) containing bis -allylic carbons are highly susceptible to lipid peroxidation [37], and recent findings suggest that a wide range of PUFAs may be involved in the ferroptosis pathway [15]

Thiamine has a protective effect against the development of the atherosclerotic plaque because it boosts endothelial functions and retards atherosclerosis progression [129]

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