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Nat Rev Immunol 14:166180

Solution: bypass the toll booth (take methylfolate directly instead of folic acid, so Step 2 is skipped entirely the cars go around the toll booth on a newly built bypass lane) AND hire more staff at the booth (supplement riboflavin the cofactor the MTHFR enzyme itself needs to function, stabilizing the booth so it processes faster even while some cars take the bypass)

Bacteriostatic Water: This is sterile water mixed with 0.9% benzyl alcohol, which acts as a preservative

This superficial location makes them vulnerable to repetitive strain but also makes them accessible for local treatment approaches

Expected timeline: This protocol suits people who prefer a non-invasive, low-commitment approach