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Toborek M and Hennig B (1996)

It also is necessary for red blood cell production

(34300194) The main barriers are logistics: A ketogenic tube feed formulation is required (many hospitals may not have this)

With RF skin tightening, low-frequency radio waves are used to heat the layers of the skin that stimulate collagen production

This could suggest that higher doses of pramlintide might be necessary to achieve significant weight loss, although it is not yet clear whether concurrent insulin treatment was the main cause of that difference