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Cirrhotic patients suffer not only from liver disease itself, but also from decreased quality of life in the form of poor work performance and an increased risk of accidents

doi: 10.2174/1381612823666170622095324

The most notable sources include: Watermelon : Contains the highest natural concentration of L-citrulline Cucumbers : Provide moderate levels of this amino acid Pumpkins and Squashes : Offer smaller but notable amounts of L-citrulline Bitter melons : Another vegetable source known for its L-citrulline content Physiological Role of L-Citrulline L-citrulline supports several important functions in the body, such as: Nitric Oxide Production : L-citrulline converts to L-arginine in the kidneys, which then supports the bodys nitric oxide production

For example, fish consumption led to higher quantities of TMAO metabolites than eggs or beef

Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities