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It is estimated that for the commonly used dosing regimen, the antidepressant response to ketamine corresponds to occupancy of approximately 30% of the total NMDAR pool in forebrain [162]

Opioid overdose comes in many forms and is not always obvious

Studies performed in guinea pigs further elucidate the potential mechanisms by which vitamin C may prevent and/or treat opioid tolerance and dependency

Unlike other antioxidants that operate independently, glutathione acts as a central regulator, directly influencing the activity of other antioxidants

In this study we confirmed that not only collagen type 1 but also CCN4 and LOX are upregulated by ENPP2