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Udovin, L

A study in Iranian patients with leptospirosis treated with ceftriaxone, a -lactam antibiotic, with or without prednisolone, showed no beneficial effect on the evolution of leptospirosis except for a shorter recovery from the thrombocytopenia, a hallmark of leptospirosis [38]

If inflammatory mediators induce tissue damage, then the structural integrity of the esophagus (e.g

39 Products of lipid peroxidation are also increased in plasma in smokers with COPD, particularly during exacerbations, resulting in DNA damage and airway epithelial cell senescence and apoptosis

To further characterize the feature of new OL genesis during whole course of this model, we further took the advantage of our recently identified OL lineage cell stage-specific marker, ENPP6, a choline-specific ecto-nucleotide pyrophosphatase /phosphodiesterase (ENPP), which is highly expressed in newly-forming/formed OLs and at a much lower levels in these more mature/old (earlier-formed) myelinating OLs (to the extent that the ISH signal would easily disappear if the development time were shortened), but not at all in OPCs, neurons, astrocytes or vascular endothelial cells (Xiao et al., 2016