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This interaction triggers the assembly of a signaling complex that includes interleukin-1 receptor-associated kinases and TNF receptor-associated factor 6, leading to the activation of nuclear factor kappa B (NF-B) and mitogen-activated protein kinases (MAPKs) such as p38 and JNK [128]

2020;21:e928499

Researchers are particularly interested in Dihexa because of its interaction with the hepatocyte growth factor (HGF)/c-Met signaling pathway

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