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Dementia-like disease, including episodes of psychosis, is possible with more severe and chronic deficiency

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Research on MOTS-c in ovariectomized mice (a model for postmenopausal metabolic dysfunction) showed reduced fat accumulation in white adipose tissue, increased brown fat activation, and improved insulin sensitivity after just 5 weeks of treatment

This shortfall can cause ongoing tiredness and hinder mental performance, making day to day life feel more challenging
