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Asrani, V

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We strongly encourage consulting with a qualified healthcare professional for advice and guidance regarding their health concerns and medication needs

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3.2.4 Conclusion for the Role of the Immune System in PD Animal Models These animal models provide substantial support for the hypothesis that the immune system participates in the neurodegeneration observed in PD

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Disruption of the Hedgehog signaling pathway can drive macrophages to prioritize glycolysis over fatty acid oxidation, effectively shifting them from an M2 phenotype to an M1-like phenotype

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