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2c), most cells in GCGR-deficient mice were mTOR and p-STAT3-S727 positive and accompanied by elevated VGF levels and hypersecretion of glucagon (Fig

The study appears online in the journal Nature Communications

A.HornungM.SattlerC.SteinbauerM.AnthuberM.ObermeierF.et al (2005)

Because of lack of renal clearance, serum values rose to more than a hundredfold from 422 pmol/L on average to 54 000 pmol/L, with 67 000 pmol/L as highest value, without side-effects

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