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The main proposed mechanisms for the protective actions of xanthines and caffeine in this context include the antagonism of the adenosine A2A receptor (ADORA2A) and inhibition of monoamine oxidase type B (MAO-B)

Arainga, M

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Hepatic failure emerges (encephalopathy, jaundice, coagulopathy, hypoglycemia, lactic acidosis, shock)

HIF-2 has been proposed to alleviate inflammation in certain contexts by reducing intracellular iron overload and limiting ferroptosis