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Epilepsy and many other illnesses for which AEDs are prescribed are themselves associated with morbidity and an increase risk of suicidal thoughts and behavior

Although anecdotal reports have long noted the significance of this dysphoric aspect of alcohol withdrawal, recent clinical studies have used a number of assessment instruments to better quantify the subjective anhedonic/dysphoric state that has been shown, in many cases, to endure for a protracted period of time during abstinence (Janiri et al., 2005

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