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In contrast to injury-driven lymphangiogenesis, which is promoted by the release of VEGF-C by inflammatory cells 26 , in this micropocket assay an inflammatory response is not a prerequisite for neovascularization 27 and can therefore be used to determine the direct effect of VEGF-A on lymphangiogenesis 26

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Every case from arm I was matched for gender, age (1 year range was allowed between the selected patients), and BMI Z score (1 SD range was allowed between them) with a patient from arm II to serve as controls

As I sat in a caf by the water, I could see behind me the solidified river of black lava that had flowed to the ocean, and the series of rock pools it had created, where groups of children were now shrieking and splashing about