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An overview on ashwagandha: A rasayana (rejuvenator) of Ayurveda

In the DHEA-induced PCOS model, recent studies have identified a distinctive triple aberration in bile acid metabolism: a marked increase in 3--OH-7-O-5-CA (signaling hyperactivation of the CYP7A1-mediated classical synthesis pathway) (Xing et al., 2023)

With intramuscular injections of B12, any excess will result in high levels within your blood so you may experience side effects such as headache, dizziness, tiredness, or gastrointestinal issues including nausea, until your body has metabolised any excess through your kidneys enroute to excretion via urine

doi: 10.3390/antiox10010074

As such, it has been linked to the development of autoimmune thyroiditis