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[7] Early detection and treatment prevent irreversible complications

In chondrocytes, ferroptosis occurs primarily due to oxidative stress, iron overload, and impaired antioxidant defense mechanisms such as reduced activity of glutathione peroxidase 4 (GPX4) and the cystine/glutamate antiporter system Xc

Exploration and studies of NRF2 activators against amyloid- may result in the development of new effective drugs against AD

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