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Similar content being viewed by others Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in progressive weakness and selective degeneration of the motor neurons, leading to death from respiratory failure within 34 years [1]

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The current study has its own limitations, no comparisons were made with patients on traditional AEDs or placebo and the short follow up duration are among these limitations

Mechanistically, DES is caused by a combination of mechanical impairment of the lids [65] and autoantibodies targeting the thyroid-stimulating hormone receptors on the lacrimal gland [66]
