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In the head-to-head SURMOUNT-5 trial (NEJM 2025), tirzepatide produced 20.2% weight loss vs 13.7% for semaglutide

At this stage, the MRI shows an anterior CSF space that is not obliterated

And, as I'm sure you've noticed, the news spends a lot of time on their plight
The absence of manufacturing oversight increases exposure to compounds of unverified quality

the most common are autoimmune diseases and diabetes
