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Washington, DC: ASM Press (2006)

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Genetic polymorphisms of CYP2D6 increase the risk for recurrence of breast cancer in patients receiving tamoxifen as an adjuvant therapy

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Additionally, the efficacy of the tested therapy depended on the dose of the anti-VEGF agent: lower doses of anti-angiogenic agent were superior to higher doses in augmenting the infiltration of tumor with CD4+ and CD8+ T-cells and in polarizing tumor-associated macrophages, from immunosuppressive M2 towards immunostimulatory M1 phenotypes

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