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Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations

Global lysine acetylation was not changed by diet or genotype (Fig

SAM acts as a methyl donor for multiple chemicals in the body, including DNA and RNA

We examined the intact A-D LBD dimer of the partially ruptured structure and noted that, while the general orientation is similar to that seen in the fully intact state, a re-shaping of the dimer interface occurs, which includes tightening along the D2-D2 surface and a ~ 5 inter-subunit rotation (Fig