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4.5 g/d: 1.7 to 2.0 cm) the 1.5 g/d study group displayed acute increases of thigh girth of 1.3 cm both at baseline testing and after four-weeks of supplementation

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According to a different study by Wilck et al., eating a lot of salt impacts the gut microbiota, mainly by decreasing Lactobacillus murinus and raising Th17 cells and blood pressure

The supplement may also interact with certain chemotherapy drugs, so cancer patients should always discuss supplementation with their oncologist before use