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With extensive knowledge of cardiology pathways and administrative processes, Sue plays a key role in facilitating appointments, investigations, and ongoing patient communication, helping to deliver a seamless and positive patient experience

TABLE 1 Advantages and disadvantages of 2D and 3D-cell cultures as model of neurodevelopmental and neurodegenerative diseases and mitochondrial disorders

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JBSNF-000088, a small-molecule analog of NA, is able to be bound to NNMT and to be methylated in the NNMT structure, with SAM being correspondingly demethylated to SAH [58]

Acknowledgements This study was supported by NIH Grant NS42617