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10.1158/1078-0432.CCR-05-0950 Clin

For each condition, at least 100 cells from randomly chosen fields were observed

ZelanteTDe LucaABonifaziPMontagnoliCBozzaSMorettiSet alIL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

Another study found that TMP via intracranial administration was able to prevent the cognitive behavioral phenotype of diabetes by modulating the SIRT1/Nrf2/HO-1 pathway, increasing the concentrations of GSH and SOD, as well as decreasing the content of mitochondrial DNA in the hippocampus of STZ-AD mice (119)

Studies also showed that lower GPx activity may increase the risk of developing AMD [83]