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You might feel a brief sting from the needle, but discomfort should be minimal

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Conclusions Short-acting bronchodilators (SABA or SAMA), but not ICS, remain initial drug therapy for COPD

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Continuing through this plateau typically leads to resumed improvement

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Apnea events are usually terminated by a microarousal due to growing chemical and mechanical cues from the body, such as falling oxygen levels, rising CO 2 , and the increased effort to breathe

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