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Not surprisingly, many ALDHs in evolutionarily distant, and seemingly unrelated, species perform similar functions, including protection against a variety of environmental stressors like dehydration and ultraviolet radiation

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Invest Ophthalmol Vis Sci 41(10):31763182 Kuriyama H, Waki M, Nakagawa M, Tsuda M (2001) Involvement of oxygen free radicals in experimental retinal ischemia and the selective vulnerability of retinal damage

PI3K: phosphatidylinositol-4,5-bisphosphate 3-kinase