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Probably, the peptides can exhibit different specificities against microorganisms, as observed in mice [151], or the expression level of the -defensin genes along the intestinal tract shows large variations to optimize the local regulation of bacterial colonization [153]

DSIP Structure CAS Number (human DSIP): 62568-57-4 (Note: Different variants may have alternate CAS identifiers) Molecular Formula: CHNO Molecular Weight (average): ~848.8 g/mol Monoisotopic Mass (exact): ~848.3 Da Parent Compound: Delta Sleep-Inducing Peptide (DSIP), a naturally occurring nonapeptide studied for its involvement in sleep-related signaling and neuroendocrine regulation pathways

thus, resistant peptic ulcers equal to resistant chronic skin ulcers, both unable to heal (Skorjanec et al., 2009)