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The excess production of ROS is one of the main molecular causes that contributes to varicocele-related male infertility, in which MIR210HG and MLLT4-AS1 (hypoxia-related lncRNAs) also showed significant positive correlations with ROS and negative correlations with sperm count and motility [48]

Additionally, chronic inflammation is a factor that has an equal, if not greater, role in the development of this disease (Geovanini and Libby, 2018)

The importance of cytokines, chemokines and nitric oxide in pathophysiology of migraine

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