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These complexes are endocytosed via lowdensity lipoprotein receptorrelated protein 1 (LRP1) receptormediated endocytosis, thereby augmenting TLR9 activation and amplifying immune responses [124]

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doi: 10.1007/s11033-014-3241-3 160 ScafaroA

As the detection system is based on visual changes in the solution hues, the LAMBDA 950 UV/Vis/NIR Spectrophotometer by PerkinElmer was employed in absorbance mode to quantify the max peak wavelength shifts

a , Scheme of the in vitro sgRNA competition assay performed in HEK-293T SLC25A39 knockout cells expressing a vector control or SLC25A39 cDNA transduced with a pool of 5 control sgRNAs (sgControl, gray) and sgRNAs targeting TXNRD2 (pink) and SLC25A40 (green) (left)