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It is, infact, able to react with hydroperoxides of fatty acids esterified in the phospholipids (23, 24)

Administration of vitamin B 12 to patients with elevated serum homocysteine levels has not been shown to reduce cardiovascular outcomes in high-risk patients or alter the cognitive decline of patients with mild to moderate Alzheimer disease

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Unlike genomic or proteomic approaches that capture upstream pathology, metabolomics reveals real-time functional alterations, which may precede structural brain changes, particularly relevant in conditions such as AD

For example, heparinase, an enzyme that degrades heparan sulphate and enhances the invasive and metastatic capacity of cancer cells, was reported to be activated by s -cysteinylation