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Description
In turn, the impairment in -oxidation can shift the metabolism of VPA toward predominantly peroxisomal -oxidation, resulting in excessive production and accumulation of -oxidation products, including 4-en-VPA a metabolite that is incriminated in VPA-induced hepatotoxicity

Med Hypotheses

Garduo-Garcia J de J, Alvirde-Garcia U, Lpez-Carrasco G, Padilla Mendoza ME, Mehta R, Arellano-Campos O, et al

Additionally, pseudotime analysis verified that these changes influenced CD4 T cell maturation (Trajectory A) and proliferation (Trajectory B) without elevating inflammatory responses

Introduction Immune thrombocytopenia (ITP) is characterized by low peripheral blood platelet count