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Additionally, PKM2 seems to play an important role in EC function and angiogenesis as silencing of PKM2 resulted in decreased sprouting (Gmez-Escudero et al., 2019), but also in reduced VE-cadherin expression resulting in destabilization of the cellular junctions (Gmez-Escudero et al., 2019)

doi: 10.3390/nu9030308

The amount of data is increased in comparison to centralized clinical trials, collected at multiple points in time, or continuously

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