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It promotes inflammation via NF-B pathway activation (82) and by activating the NLRP3 inflammasome in endothelial cells and arterial walls in mice, involving mitochondrial ROS, TXNIP, and lysosomal instability (101, 134)

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Psychiatric comorbidity in 36 adults with mitochondrial cytopathies

The gold standard for a celiac diagnosis is a biopsy of the small intestine demonstrating flattened villi (Guandalini 2014

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