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Unlike some vitamins, B12 is absorbed through the digestive system, which means some people struggle to absorb enough from food alone

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The objective of the Barnes maze test was to let a mouse explore the space and memorize the location of the escape box using the configuration of distal visual cues placed around the testing area

This method is particularly effective for people with vitamin B12 deficiency, which is common in older adults, vegetarians, and individuals with certain medical conditions

(PMID: 34827486) and the broader systematic review by Ho and Nation (PMID: 29733881) provide some supporting evidence from outside the affected research group