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8-OHdG can be excised from the DNA during repair mechanisms, thus being released in the blood stream and subsequently be excreted in the urine, patients-derived biofluids where it can be detected (Lunec et al., 2002)

From there, a structured nutrition plan and individualized evaluation can help clarify next steps

MEVs can contain antigens that activate Toll-like receptors on epithelial or immune cells and increase blood-brain-barrier (BBB) permeability, thus facilitating the entry of bacterial byproducts in the brain (26, 29)