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Mammalian macroautophagy degrades various substrates, including damaged organelles, dysfunctional proteins, and invading pathogens [141]

86 Similarly, metabolomic analyses have characterized molecular changes in CFE reactions due to variations in extract source strain growth media and harvest conditions, 87 the impact of metabolites on CFE, 88 metabolic flux over time in differentially lysed extracts, 89 and batch-to-batch variability

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