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The TKT gene is located on chromosome 3p21.1 and is composed of 15 exons that generate three alternatively spliced mRNAs that collectively encode two distinct protein isoforms

Clinical translation will require well-controlled dietary and microbial interventions aimed at selectively modulating metabolite production during critical developmental periods

doi: 10.1016/j.expneurol.2007.05.014

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159 Despite synthetic polymers-based NPs with numerous benefits, there are still a couple of concerns about potential toxicity