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In WT mice, although cagrilintide treatment led to significant weight loss, the changes in body composition compared to vehicle-treated mice did not reach statistical significance, with fat mass decreasing by 7% ( P = 0.2) and lean mass increasing by 5% ( P = 0.14

Spectral quantification of Glu at 2.35ppm was performed using LCModel after acquiring basis spectra from a phantom with known concentrations of relevant metabolites

The irradiated EBV transformed lymphoblastoid cell line (LCL) was utilized as a cellular vaccine

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