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10.1016/j.ebiom.2022.104258 66 LvM.CaiY.HouW.PengK.XuK.LuC.et al (2022)
For people who are sensitive to GI side effects, slower titration generally produces better tolerability
several herbals are discussed, including comfrey, Jin Bu huan, germander, chaparral leaf, skullcap and valerian, but not ashwagandha)
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However, in healthy volunteers, 72 h of fasting significantly increased cortisol and norepinephrine in the blood and was accompanied by an increase in somatic depressive symptoms assessed by Becks Depression Inventory (BDI)-2 sum-score (45)
