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These included glucose and insulin tolerance tests to define whole-body glucose homeostasis, 13 C-isotope tracing in conscious unrestrained mice to determine the tissue-specific fate of glucose and serine in vivo , and metabolomics to quantify metabolite concentrations

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JBSNF-000088, a small-molecule analog of NA, is able to be bound to NNMT and to be methylated in the NNMT structure, with SAM being correspondingly demethylated to SAH [58]

Data from the National Health and Nutrition Examination Survey (NHANES) estimated that the prevalence of DKD in the United States was 14.35% in 2020, with a projection of 16.7% by 2030

Our previous study shows that ferroptosis is a potential pathway in the pathology of SS [23]