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Conditions like CRPS, fibromyalgia, and neuropathic pain involve central sensitization, where the nervous system amplifies pain signals beyond the original injury

The spectrum ranges from complete remission (frequently obtained within the first 3 years) and totally normal intellectual development to therapy resistant epilepsy with severe cognitive disability (5,21,24,29)

But the preclinical data, combined with growing clinical observations, suggests these compounds may support disc healing through mechanisms that conventional treatments simply do not address

The thioredoxin system as a therapeutic target in human health and disease