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Symptoms of vitamin B12 deficiency Some of the symptoms that can be caused by a lack of vitamin B12 include: Poor appetite Anemia Fatigue Weakness Numbness or tingling in the hands or feet Difficulty with balance Vitamin B12 deficiency can also contribute to depression, cognitive impairment, and dementia

G protein-coupled receptor trafficking and signaling: new insights into the enteric nervous system

It is important to note that while many biochemical studies provide support for the disparate structure of these FeS clusters in Rrf2 proteins, crystallographic structures have only been reported for holo-NsrR 498 and RsrR

Step 3: Follow Up Depending on your deficiency level, your doctor may recommend regular injections for a set period of time

So if you have any of the below symptoms, you most likely need B12