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Autophagy in cancer resistance to paclitaxel: Development of combination strategies

As a consequence, GDH flux (Figure 1, ) increases [5] supplying anaplerosis as malate exits the cycle forming pyruvate which in turn supports citrate formation (Figure 2)

10.1038/s41586-018-0356-z 130 YaoC.WilsonM

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It is designed with the aim to modify the microbiome and microbe-associated metabolites in the gastrointestinal tract to modulate pathways linked to gastrointestinal inflammation and to improve epithelial barrier integrity in patients with ulcerative colitis