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Recent studies have identified the gut and oral microbiomesthrough their metabolism of dietary precursors into trimethylamine (TMA) and its hepatic conversion to trimethylamine-N-oxide (TMAO)as pivotal contributors to CVD risk
HNE produces different effects: acts as an intracellular signal able to modulate gene expression, cell proliferation, differentiation and apoptosis

These amino acids are called essential amino acids because our body is not able to synthesize them
Without sufficient carnitine, fatty acid oxidation is impaired, potentially leading to energy deficits
