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However, it is not entirely certain how many of these patients met ME/CFS criteria, suggesting that replication studies should be done in future to help us understand the genes, cellular processes, and tissues or cells that causally change the risk for developing ME/CFS

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Olpasiran (AMG890) has shown a dose-dependent significant reduction in Lp(a) concentrations [235], OCEAN(a)-Outcome (NCT05581303) is an ongoing phase III clinical trial designed to study its long-term effects on MACE

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